Incorporating remote visits into an outpatient clinic

Copyright @ 2009 Operational Research Society Ltd. This is a post-peer-review, pre-copyedit version of an article published in Journal of Simulation. The definitive publisher-authenticated version Eatock and Eldabi (2009), "Incorporating remote visits into an outpatient clinic", Journal of Simulation, 3, 179–188 is available online at the link below.Most telemedicine studies are concerned with either the technological or diagnostic comparisons, rather than assessing the impact on clinic management. This has attributed to the retrospective nature of the studies, with lack of data being the main cause for not using simulation for prospective analysis. This article demonstrates the use of simulation to assess the impact of prospective systems by utilising data generated from clinical trials. The example used here is the introduction of remote consultations into an outpatient's clinic. The article addresses the issues of using secondary data, in terms of the differences between the trial, the model and future reality. The result of running the simulation model show that exchanging the mode of service delivery does not improve patient wait times as expected, and that a protocol change in association with the introduction of remote visits is necessary to provide a substantial reduction in patient wait times

The complexity and generality of learning answer set programs

Traditionally most of the work in the field of Inductive Logic Programming (ILP) has addressed the problem of learning Prolog programs. On the other hand, Answer Set Programming is increasingly being used as a powerful language for knowledge representation and reasoning, and is also gaining increasing attention in industry. Consequently, the research activity in ILP has widened to the area of Answer Set Programming, witnessing the proposal of several new learning frameworks that have extended ILP to learning answer set programs. In this paper, we investigate the theoretical properties of these existing frameworks for learning programs under the answer set semantics. Specifically, we present a detailed analysis of the computational complexity of each of these frameworks with respect to the two decision problems of deciding whether a hypothesis is a solution of a learning task and deciding whether a learning task has any solutions. We introduce a new notion of generality of a learning framework, which enables us to define a framework to be more general than another in terms of being able to distinguish one ASP hypothesis solution from a set of incorrect ASP programs. Based on this notion, we formally prove a generality relation over the set of existing frameworks for learning programs under answer set semantics. In particular, we show that our recently proposed framework, Context-dependent Learning from Ordered Answer Sets, is more general than brave induction, induction of stable models, and cautious induction, and maintains the same complexity as cautious induction, which has the highest complexity of these frameworks

Minimally Invasive Transverse Aortic Constriction in Mice

Minimally invasive transverse aortic constriction (MTAC) is a more desirable method for the constriction of the transverse aorta in mice than standard open-chest transverse aortic constriction (TAC). Although transverse aortic constriction is a highly functional method for the induction of high pressure in the left ventricle, it is a more difficult and lengthy procedure due to its use of artificial ventilation with tracheal intubation. TAC is oftentimes also less survivable, as the newer method, MTAC, neither requires the cutting of the ribs and intercostal muscles nor tracheal intubation with a ventilation setup. In MTAC, as opposed to a thoracotomy to access to the chest cavity, the aortic arch is reached through a midline incision in the anterior neck. The thyroid is pulled back to reveal the sternal notch. The sternum is subsequently cut down to the second rib level, and the aortic arch is reached simply by separating the connective tissues and thymus. From there, a suture can be wrapped around the arch and tied with a spacer, and then the sternal cut and skin can be closed. MTAC is a much faster and less invasive way to induce left ventricular hypertension and enables the possibility for high-throughput studies. The success of the constriction can be verified using highfrequency trans-thoracic echocardiography, particularly color Doppler and pulsed-wave Doppler, to determine the flow velocities of the aortic arch and left and right carotid arteries, the dimension of the blood vessels, and the left ventricular function and morphology. A successful constriction will also trigger significant histopathological changes, such as cardiac muscle cell hypertrophy with interstitial and perivascular fibrosis. Here, the procedure of MTAC is described, demonstrating how the resulting flow changes in the carotid arteries can be examined with echocardiography, gross morphology, and histopathological changes in the heart.Department of Health Technology and Informatics2016-2017 > Academic research: refereed > Publication in refereed journalbcr

Abstract book : 25th IVR World Congress of Philosophy of Law and Social Philosophy ; law, science, technology ; 15 – 20 August 2011, Frankfurt am Main, Germany

On behalf of myself and my colleagues Professor Dr. Klaus Günther and Professor Dr. Lorenz Schulz, it is my great pleasure to welcome you to the 25th World Congress of the International Association for Philosophy of Law and Social Philosophy (IVR) in Frankfurt am Main. ...Auch im Namen meiner Frankfurter Kollegen Prof. Dr. Klaus Günther und Prof. Dr. Lorenz Schulz möchte ich Sie zu dem 25. Weltkongress der Internationalen Vereinigung für Rechts- und Sozialphilosophie (IVR) in Frankfurt am Main sehr herzlich begrüßen. ..

Synthesis of compact wind profiles using evolutionary algorithms

In this paper, the authors face the problem of wind speed processing as environmental variable of a wind turbine system. Generally, the information on wind speed measurements is processed over long periods of time to be relevant with respect to the site characteristics (average and maximum speeds, statistics). Subsequent large scale profiles of wind speed lead to long processing time for simulation analysis and especially for optimization design that penalizes the search of optimal solutions. An original synthesis approach of a compact and representative wind speed profile using an Evolutionary Algorithm (EA) is proposed. This approach is compared to a purely statistical approach based on random number generators. It allows reducing the actual wind profile duration with compression ratios greater (two months of wind speed measurements are compressed in only 1 hour). Then, the synthesis approach by EA is applied to the sizing of an autonomous hybrid system based on wind turbine with battery storage for stand-alone energy systems. It has proven its effectiveness in reducing 200 days of wind speed measurements in only 10 days, allowing sizing the storage system with a significant gain in terms of computing time in the framework of the optimization process

Circulating pigment epithelium-derived factor levels and the risk of hypertension in a community-based study

Oral Session 2 – Translational & Clinical Research (I)published_or_final_versionThe 16th Medical Resarch Conference (MRC), The University of Hong Kong, Hong Kong, China, 22 January 2011. In Hong Kong Medical Journal, 2011, v. 17, suppl. 1, p. 15, abstract no. 1